Schreiner MediPharm develops Freeze-Lock label

The novel Freeze-Lock label consists of the bottom layer with a specialty microfine surface texture applied to the empty, non-refrigerated container at room temperature. Subsequently, the container is filled with the active ingredient and immediately cooled down for storage at sub-zero temperatures of dry ice (-78 °C) or liquid nitrogen (-196 °C). To mark the frozen container, it is removed from cold storage. 

The top layer is dispensed onto it and firmly pressed against the bottom label; a potential layer of ice does not have to be removed. The deep freeze adhesive of the top label combines with the texture of the bottom label and freezes in a matter of seconds. This results in a permanent bond between the label construction and the container that can be returned to storage and transported in frozen condition.

Due to the specialty two-component label design and the materials and adhesives used, the Freeze-Lock cryo label reliably adheres to the frozen container; important product information cannot be lost. 

Pharmaceutical and biopharmaceutical manufacturers and users in clinical research will benefit from a customized and efficient marking technology for frozen medications that can be adapted to a wide range of applications.